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S4881

Sigma-Aldrich

Staphylococcal enterotoxin B from Staphylococcus aureus

Synonyme(s) :

Enterotoxin B, Staphylococcal, SEB

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1 MG
321,00 €
5 MG
1 230,00 €

321,00 €

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Devis pour commande en gros
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Changer de vue
1 MG
321,00 €
5 MG
1 230,00 €

About This Item

Numéro CAS:
11100-45-1
Numéro MDL:
MFCD00082017
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.25

321,00 €

Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.
Devis pour commande en gros

Contient

sodium phosphate buffer as balance

Niveau de qualité

300

Composition

Protein, ~25% Lowry

Disponibilité

not available in USA

Impuretés

Staphylococcal enterotoxin A (SEA), essentially free

Application(s)

metabolomics
vitamins, nutraceuticals, and natural products

Température de stockage

2-8°C

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Application

Staphylococcal enterotoxin B (SEB) which binds to MHC class II molecules and specific Vβ regions of T cell receptors (TCR), resulting in the activation of both monocytes/macrophages and T lymphocytes may be used as a superantigen and immune system activator. SEB may be used as a reference material in the development of SEB detection systems.

Actions biochimiques/physiologiques

A superantigen for T-lymphocytes. Activator of the immune system that binds to major histocompatibility complex (MHC) antigens[1] and CD28.[2]

Conditionnement

Package size based on protein content.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

08168

Timestrip Plus™ 8 °C

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
0000103755
0000209972
0000103755
11181129
0000209972

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Consulter la Bibliothèque de documents

Clarifying the mechanism of superantigen toxicity.
John D Fraser
PLoS biology, 9(9), e1001145-e1001145 (2011-09-21)
Oliver G Weingart et al.
Sensors (Basel, Switzerland), 12(2), 2324-2339 (2012-03-23)
Prevalent incidents support the notion that toxins, produced by bacteria, fungi, plants or animals are increasingly responsible for food poisoning or intoxication. Owing to their high toxicity some toxins are also regarded as potential biological warfare agents. Accordingly, control, detection
Winnie Bergstedt et al.
PloS one, 5(6), e11277-e11277 (2010-07-02)
Tuberculin is still the only available skin test reagent for the diagnosis of mycobacterial infection. The product has a remarkable sensitivity, but poor specificity. Previous studies, including two human phase I clinical trials, have indicated that rdESAT-6 has a potential
Bacterial superantigens
Proft, T. and Fraser, J.D.
Clinical and Experimental Immunology, 133, 299-299 (2008)
Iria Gomez-Tourino et al.
Nature communications, 8(1), 1792-1792 (2017-11-28)
Defects in T cell receptor (TCR) repertoire are proposed to predispose to autoimmunity. Here we show, by analyzing >2 × 10
Afficher tous les articles scientifiques apparentés

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. こんにちは、この商品の容量をお聞きしたいのですが、1MGと表記されている場合、1miligramということでしょうか？ 溶かしてから調剤したいのですが。 溶かして調剤する際のプロトコルはあるのでしょうか？

    1 answer

    1. Yes, the 1MG does stand for one milligram. The product is soluble in water at 4 mg/ml. It may also be dissolved in an aqueous buffer such as PBS. See the link below to the product information sheet for additional solution stability information:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/126/857/s4881pis.pdf

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