S1885

Suberic acid bis(N-hydroxysuccinimide ester)

≥95%, powder

• Synonyme(s) : Disuccinimidyl suberate, Disuccinimidyl octanedioate, Disuccinimidyl suberate (DSS)
• Formule empirique (notation de Hill): C₁₆H₂₀N₂O₈
• Numéro CAS: 68528-80-3
• Poids moléculaire : 368.34
• Numéro MDL: MFCD00049059
• Code UNSPSC : 12352100
• ID de substance PubChem : 24899500
• Nomenclature NACRES : NA.21

Propriétés

• Pureté: ≥95%
• Forme: powder
• Pertinence de la réaction: reagent type: cross-linking reagent
• Solubilité: chloroform: 50 mg/mL; DMF: soluble; aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.)
• Température de stockage: 2-8°C
• Chaîne SMILES: O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
• InChI: 1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2
• Clé InChI: ZWIBGKZDAWNIFC-UHFFFAOYSA-N

Description

Description générale

Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.

Application

Suberic acid bis(N-hydroxysuccinimide ester) has been:

• supplemented in pierce lysis buffer used for immunoprecipitation
• used to conjugate the oligonucleotide standards to gelatin
• used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)