RAB1320

Human Cathepsin Z ELISA

for serum, plasma and cell culture supernatants

• Code UNSPSC : 12352200

Propriétés

• Espèces réactives: human
• Technique(s): ELISA: suitable
• Entrée: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: human ... CTSZ(1522)

Description

Description générale

Cathepsins are normally localized in lysosomes of almost all mammalian cells, but under certain conditions they can be secreted from the cells that take part in local proteolysis.[1][2] Cathepsin Z is a cysteine protease, predominantly expressed in immune cells including monocytes, macrophages or dendritic cells.[3][4][5]

This ELISA antibody pair detects Human Cathepsin Z (CTSZ/Cathepsin X/Cathepsin P)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Actions biochimiques/physiologiques

Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis.[6] Cathepsin Z is known to be associated with the pathogenesis of cancer and promotes the development and proliferation of tumor cells. Cathepsin Z mediates the process of proliferation, migration, maturation, adhesion, signal transduction and phagocytosis of immune cells.[3][4][5]

Autres remarques

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Warning
• Mentions de danger: H290
• Conseils de prudence: P234 - P390
• Classification des risques: Met. Corr. 1
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable