PLA0296

Goat anti-FUS Antibody, Affinity Purified

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• Synonyme(s) : 75 kDa DNA-pairing protein, ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, amyotrophic lateral sclerosis 6, derived from t(12;16) malignant liposarcoma, fus-like protein, fused in sarcoma, fusion, fusion (involved in t(12;16) in malignant liposarcoma), fusion gene in myxoid liposarcoma, heterogeneous nuclear ribonucleoprotein P2, hnRNP-P2, oncogene FUS, oncogene TLS, translocated in liposarcoma, translocated in liposarcoma protein
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: goat
• Niveau de qualité: 100
• Forme d'anticorps: affinity purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Espèces réactives: human, mouse
• Technique(s): immunohistochemistry: 1:500-1:2,000; immunoprecipitation (IP): 2- 10 μg/mg; western blot: 1:2,000- 1:10,000
• Numéro d'accès: P35637
• Numéro d'accès UniProt: P35637
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: goat ... FUS(2521)

Description

Immunogène

The epitope recognized by PLA0296 maps to a region between residue 1 and 50 of human Fusion (involved in t(12;16) in malignant liposarcoma) using the numbering given in entry P35637 (GeneID 2521).

Forme physique

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Autres remarques

FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable