P6744

Acide picrique solution

1.3% in H₂O (saturated)

• Synonyme(s) : 2,4,6-Trinitrophenol
• Formule linéaire : (O₂N)₃C₆H₂OH
• Numéro CAS: 88-89-1
• Poids moléculaire : 229.10
• Numéro Beilstein : 423400
• Numéro MDL: MFCD00007102
• Code UNSPSC : 12171500
• ID de substance PubChem : 24898790
• Nomenclature NACRES : NA.47

Propriétés

• Forme: liquid
• Concentration: 1.3% in H₂O (saturated)
• Couleur: yellow to very dark yellow
• Densité: 1.080 g/cm³
• Application(s): hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: Oc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O
• InChI: 1S/C6H3N3O7/c10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h1-2,10H
• Clé InChI: OXNIZHLAWKMVMX-UHFFFAOYSA-N

Description

Description générale

Picric acid is a polynitrated aromatic acid. It dissolves in water to form a solution with low pH (pH 2.0). It interacts with basic groups of proteins, forms salts and coagulates them. Fixation with picric acid gives a bright stain, but there might be a loss of nucleic acids due to the low pH of the solution.
Picric acid is anionic and has a low molecular weight.

Application

Picric acid is commonly used as a fixative and staining reagent in forensic and histological applications. It is a general cytoplasmic stain, connective tissue fiber stain, and a fixative for tissues.

• It is a component of picrosirius red which is used to stain collagen.
• Bouin’s fluid which also comprises picric acid is a fixative for nuclei and connective tissue.
• It can be used as a colorimetric reagent in creatinine determination assay.

Informations sur la sécurité

• Risques supp: EUH001
• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves