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O5501

Sigma-Aldrich

Oxyphenonium bromide

Synonyme(s) :

2-([Cyclohexylhydroxyphenylacetyl]oxy)-N,N-diethyl-N-methylethanaminium bromide

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About This Item

Formule linéaire :
C21H34NO3Br
Numéro CAS:
50-10-2
Poids moléculaire :
428.40
Numéro CE :
200-010-7
Numéro MDL:
MFCD00050259
Code UNSPSC :
12161900
ID de substance PubChem :
24898019

Description

cationic

Pureté

>98% (TLC)

Poids mol.

428.40 g/mol

Chaîne SMILES 

Br.CC[N](C)(CC)CCOC(=O)C(O)(C1CCCCC1)c2ccccc2

InChI

1S/C21H34NO3.BrH/c1-4-22(3,5-2)16-17-25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6,8-9,12-13,19,24H,4-5,7,10-11,14-17H2,1-3H3;1H

Clé InChI

JKJFWDDPBNHJPV-UHFFFAOYSA-N

Application

Oxyphenonium bromide has been used in a study to assess masking mechanisms of bitter taste of drugs. It has also been used in a study to investigate stoichiometric and microenvironmental effects on hydrolysis of propantheline in cyclodextrin solutions.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302 + H312 + H332

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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G I Nezhinskaya et al.
Bulletin of experimental biology and medicine, 145(1), 55-57 (2008-11-26)
Blood plasma proteins modulated the effects of muscarinic receptor antagonist methacin. Administration of methacin in combination with albumin or C-reactive protein (but not with IgG) abolished the broncholytic effect of methacin. It was probably associated with allosteric antagonism to M2
T P Berezina et al.
Bulletin of experimental biology and medicine, 147(3), 296-300 (2009-06-17)
Psychogenic stress in rabbits (fixation to a frame) was accompanied by the inhibition of contractile activity of the gastric antrum and pylorus. These changes persisted during blockade of muscarinic receptors, nicotinic receptors, alpha(2)-adrenoceptors, and beta(1)/beta(2) adrenoceptors. A stress-induced decrease in
V A Kozhevnikov et al.
Anesteziologiia i reanimatologiia, (5)(5), 15-19 (2006-12-23)
The good tolerability of sevoflurane, the mild and prompt onset of a hypnotic state, the absence of airway irritation, and the safe use of the agent make the anesthetic of choice for introductory anesthesia in pediatric cardiosurgery. The purpose of
N Ya Kovalenko et al.
Bulletin of experimental biology and medicine, 140(2), 177-180 (2005-11-12)
Experiments employing ultrasound technique showed that nonselective blockade of central muscarinic cholinoceptors with amizyl significantly increases the number and lifespan of rats highly resistant to acute massive blood loss. This pretreatment increased individual resistance of the circulatory system to posthemorrhagic
T P Berezina et al.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 91(8), 893-902 (2005-10-29)
In experiments on unanaesthetized rabbits, myoelectric activity (contractile activity index) of distal ileum, caecum, and proximal colon in two sites was studied under stress induced by fastening a rabbit to the table in supine position. The stress caused sharp decrease
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