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Merck
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Principaux documents

M221

Sigma-Aldrich

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α3 Subunit) antibody produced in rat

~5 mg/mL, clone mAb 313, affinity isolated antibody, buffered aqueous solution

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About This Item

Numéro MDL:
MFCD00677279
Code UNSPSC :
12352203

Source biologique

rat

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

mAb 313, monoclonal

Forme

buffered aqueous solution

Espèces réactives

chicken

Concentration

~5 mg/mL

Technique(s)

immunohistochemistry (frozen sections): 1:4,000

Isotype

IgG2a

Numéro d'accès UniProt

P09481

Conditions d'expédition

dry ice

Température de stockage

−20°C

Informations sur le gène

chicken ... CHRNA3(386578)

Spécificité

Binds to native and denatured detergent-solubilized α3 subunit of AchR. Does not bind α1, α4, α5, α7, α8 and β2.

Immunogène

recombinant large cytoplasmic domain of the α3 subunit (amino acids 315-441) of the nicotinic acetylcholine receptor from chick.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Forme physique

Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.

Informations légales

Sold with permission of the Salk Institute

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

P J Whiting et al.
Brain research. Molecular brain research, 10(1), 61-70 (1991-04-01)
Neuronal nicotinic acetylcholine receptors (AChRs) are composed of two types of subunits: ACh-binding (termed alpha 2, alpha 3, alpha 4 ...) and structural (termed beta 2, beta 3, beta 4 ...). AChR subtypes composed of combinations of subunits of these
W G Conroy et al.
Neuron, 9(4), 679-691 (1992-10-01)
The acetylcholine receptor (AChR) alpha 5 gene has been classified as a member of the AChR gene family based on sequence homology. Expression studies, however, have yet to identify a function for the alpha 5 gene product or even to
Benjaporn Buranrat et al.
Oncology reports, 34(5), 2790-2796 (2015-09-10)
Ferritin is a major iron storage protein and essential for iron homeostasis. It has a wide range of functions in the body including iron delivery, immunosuppression, angiogenesis, and cell proliferation. Ferritin is overexpressed in many cancer cells, but its precise
Margarita Villar et al.
Biomolecules, 10(4) (2020-04-09)
Ticks are obligate hematophagous arthropods and vectors of pathogens affecting human and animal health worldwide. Cement is a complex protein polymerization substance secreted by ticks with antimicrobial properties and a possible role in host attachment, sealing the feeding lesion, facilitating
Lindstrom
Neurotransmissions, 12, 2-2 (1996)
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