M1272
Anti-Mouse IgA (α-chain specific) antibody produced in sheep
affinity isolated antibody, lyophilized powder
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About This Item
Produits recommandés
Source biologique
sheep
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
secondary antibodies
Clone
polyclonal
Forme
lyophilized powder
Technique(s)
Ouchterlony double diffusion: suitable
Température de stockage
2-8°C
Modification post-traductionnelle de la cible
unmodified
Description générale
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Anti-Mouse IgA (α-chain specific) is specific for α chain of mouse IgA.
Anti-Mouse IgA (α-chain specific) is specific for α chain of mouse IgA.
Immunogène
Purified mouse IgA (myeloma protein)
Application
Anti-Mouse IgA (α-chain specific) is suitable for Ouchterlony Double Diffusion. The antibody was used to detect antigens to Helicobacter hepaticus in mice serum using a concentration of 5 μg/ml.
Forme physique
Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2
Reconstitution
Reconstitute with 0.135 M sodium chloride.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Mark T Whary et al.
Immunology, 133(2), 165-178 (2011-03-24)
To model inflammatory bowel disease, we assessed infection with Helicobacter hepaticus 3B1 (ATCC 51449) and a potential probiotic Lactobacillus reuteri (ATCC PTA-6475) in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(-/-) ) mice. No typhlocolitis developed in germ-free controls (n=21) or in L. reuteri (n=8)
Jan Holmgren et al.
Nature medicine, 11(4 Suppl), S45-S53 (2005-04-07)
There is currently great interest in developing mucosal vaccines against a variety of microbial pathogens. Mucosally induced tolerance also seems to be a promising form of immunomodulation for treating certain autoimmune diseases and allergies. Here we review the properties of
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