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L7635

L-α-Lysophosphatidylinositol sodium salt from Glycine max (soybean)

≥96%

Synonyme(s) :

1-Acyl-sn-glycero-3-phospho-(1-D-myo-inositol)

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Taille/RéférenceDisponibilitéPrix
1 mg
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182,00 €
5 mg
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618,00 €

A propos de cet article

UNSPSC Code:
51191904
NACRES:
NA.25
MDL number:

182,00 €


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biological source

soybean

Quality Segment

assay

≥96%

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

Application

L-α-Lysophosphatidylinositol sodium salt from Glycine max (soybean) has been used as an agonist of G protein-coupled receptor 55 (GPR55).

Biochem/physiol Actions

L-α-Lysophosphatidylinositols (LPI) functions as an endogenous ligand for putative cannabinoid receptor and G protein-coupled receptor 55 (GPR55). LPI plays a regulatory role in cell proliferation, migration and function. Increased circulatory levels of LPI has been observed in the obese patients. In addition, overexpression of LPI leads to the development of various types of cancers including ovarian and breast cancer. LPI can be used as a potential diagnostic and prognostic biomarker for ovarian cancer.
L-α-Lysophosphatidylinositols from Glycine max (soybean) are enriched with stearate and palmitate. Soybean Lysophosphatidylinositols may be compared with other lysophosphatidylinositol for biological activities which depend upon the identity of the acylated fatty acid.

Preparation Note

Prepared by the action of phospholipase A on L-α-phosphatidylinositol.

Analysis Note

Contains primarily palmitic and stearic acids.


Classe de stockage

11 - Combustible Solids

Que se passe-t-il ?

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

EPI (équipement de protection individuelle)

Eyeshields, Gloves, type N95 (US)



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Lot/Batch Number

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Questions

1–4 of 4 Questions  
  1. Wie lang ist LPI bei -20°C haltbar?

    1 answer
    1. This product is not assigned an expiration or retest date. Products that are not assigned expiration or retest dates are quite stable and are warranteed for 1 year from the date of shipment. Following reconstitution, stock solutions may be stored for up to 3 months at -20°C in working aliquots. Avoid repeated freeze/thaw cycles. Please see the link below to review additional information available in the complete Product Dating Statement:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/190/408/product-dating-information-ms.pdf?.

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  2. What is the molecular weight of L-α-Lysophosphatidylinositol sodium salt from Glycine max, Product L7635?

    1 answer
    1. We have calculated a value of 605.1, based on the structure of phosphatidyl-1-inositol and the assumption that the main fatty acids present as part of the structure are C16:0 (58%) and C18:0 and C18:2 (42%).

      Helpful?

  3. What fatty acid groups does L-α-Lysophosphatidylinositol sodium salt from Glycine max, Product L7635, contain?

    1 answer
    1. The main fatty acid group is palmitic acid.  The next most abundant fatty acid groups tend to be stearic acid and linolenic acid, and then oleic acid and linoleic acid.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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