H1541

Anti-HOXC4 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-CP19, Anti-Homeobox 3E, Anti-Homeobox C4
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~40 kDa
• Espèces réactives: human
• Concentration: ~1.0 mg/mL
• Technique(s): immunoprecipitation (IP): 5-10 μg/mL using lysates of HEK-293T cells over expressing human HOXC4; indirect immunofluorescence: 1-2 μg/mL using paraformaldehyde fixed HEK-293T cells over expressing human HOXC4; western blot: 5-10 μg/mL using lysates of HEK-293T cells over expressing human HOXC4
• Numéro d'accès UniProt: P09017
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... HOXC4(3221) ; mouse ... Hoxc4(15423) ; rat ... Hoxc4(24459)

Description

Description générale

The homeobox C4 (HOXC4) gene is mapped on the human chromosome at 12q13.13.

Spécificité

Anti-HOXC4 (C-terminal) recognizes human HOXC4 (also known as Hox-3E and CP19).

Application

Anti-HOXC4 (C-terminal) antibody produced in rabbit may be used in:

• immunoblotting
• immunoprecipitation
• immunofluorescence

Actions biochimiques/physiologiques

Homeobox C4 (HOXC4) transcription factor/protein is involved in inducing the function of activation-induced cytosine deaminase (AID). Upregulation of the HOXC4 gene is due to the estrogen-estrogen receptor complexes. HOXC4 gene is expressed in the nucleus of activated human lymphocytes and the increased expression level is observed with the progression of lymphoid differentiation.

Forme physique

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Stockage et stabilité

For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.