GW22766
Anti-FAS (ab1) antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
Synonyme(s) :
Anti-CD95
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About This Item
Source biologique
chicken
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
buffered aqueous solution
Espèces réactives
human, mouse, rat
Fabricant/nom de marque
Genway 15-288-22766
Technique(s)
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... FAS(355)
Catégories apparentées
Description générale
The FAS receptor (FasR) is a protein encoded by the TNFRSF6 gene in humans and is mapped to chromosomal band 10q24.1. It is a cell surface antigen expressed on a variety of normal and malignant cells.
Immunogène
Immunogen Sequence: GI # 4507583, sequence 21-165
Recombinant tumor necrosis factor receptor superfamily, member 6 isoform 1
Application
Anti-FAS (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Actions biochimiques/physiologiques
The FAS receptor (FasR) is associated with programmed cell death (apoptosis). It functions as an apoptosis-signaling cell surface Ag. Mutation of the gene or defective FAS signaling may render the T-cell lymphoblastic lymphomas (T-LBLs) tumor cells resistant to apoptotic cell death.
Forme physique
Solution in phosphate buffered saline containing 0.02% sodium azide.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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I Cascino et al.
Journal of immunology (Baltimore, Md. : 1950), 154(6), 2706-2713 (1995-03-15)
Fas/Apo-1 molecule is an apoptosis-signaling cell surface Ag belonging to the TNFR family. To investigate the possibility that soluble forms of the Fas receptor are expressed in human cells, we analyzed Fas mRNA transcripts obtained from activated peripheral mononuclear cells
M Villa-Morales et al.
Cell death & disease, 5, e1110-e1110 (2014-03-08)
The acquisition of resistance towards FAS-mediated apoptosis may be required for tumor formation. Tumors from various histological origins exhibit FAS mutations, the most frequent being hematological malignancies. However, data regarding FAS mutations or FAS signaling alterations are still lacking in
P Lichter et al.
Genomics, 14(1), 179-180 (1992-09-01)
The APO-1 (APT) antigen is a cell surface antigen expressed on a variety of normal and malignant cells. Binding of anti-APO-1 antibody to the APO-1 antigen induces programmed cell death (apoptosis). The APO-1 antigen shows homology to the members of
Derek L Clouthier et al.
Journal of immunology (Baltimore, Md. : 1950), 193(10), 5033-5043 (2014-10-05)
The costimulatory TNFR family member GITR can provide important survival signals for CD8 T cells. However, little is known about the regulation of this pathway during a chronic infection. In this study, we show that GITR ligand (GITRL) is maximally
Odilia B J Corneth et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(2), 340-349 (2014-02-08)
Interleukin-17A (IL-17A) signals through the IL-17 receptor (IL-17R) A/C heterodimer. IL-17RA serves as a common receptor subunit for several IL-17 cytokine family members. Lack of IL-17RA signaling may therefore have additional effects beyond those of lack of IL-17A alone. The
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