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Principaux documents

G9398

Sigma-Aldrich

Asialoganglioside-GM2 from bovine brain

~95%, lyophilized powder

Synonyme(s) :

GA2 Ganglioside, Gangliotriosyl ceramide

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.77

Essai

~95%

Niveau de qualité

Forme

lyophilized powder

Température de stockage

−20°C

Description générale

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Actions biochimiques/physiologiques

Degraded form of Asialoganglioside-GM1 ganglioside.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Christian H Schweppe et al.
Journal of lipid research, 51(8), 2282-2294 (2010-05-07)
Shiga toxin (Stx)-producing Escherichia coli are the leading cause of hemorrhagic colitis and life-threatening extraintestinal complications in humans. Stx1 and Stx2 are transferred by yet to be delineated mechanisms from the intestine to the circulation where they injure microvascular endothelial
Annelies Coddens et al.
PloS one, 6(9), e23309-e23309 (2011-09-29)
Enterotoxigenic F4-fimbriated Escherichia coli is associated with diarrheal disease in neonatal and postweaning pigs. The F4 fimbriae mediate attachment of the bacteria to the pig intestinal epithelium, enabling an efficient delivery of diarrhea-inducing enterotoxins to the target epithelial cells. There
K Tadano-Aritomi et al.
Glycoconjugate journal, 13(2), 285-293 (1996-04-01)
A novel mono-sulfated glycosphingolipid based on the gangliotriaose core structure was isolated from rat kidney. The isolation procedure involved extraction of lipids with chloroform/methanol, mild alkaline methanolysis, column chromatographies with anion exchangers and silica beads. The structure was characterized by
Kamruddin Ahmed et al.
Medical microbiology and immunology, 191(1), 5-10 (2002-07-26)
Moraxella catarrhalis is an important pathogen of respiratory and middle ear infections. We previously reported that the attachment of M. catarrhalis to pharyngeal epithelial cells is mediated by ganglioside M2 (GM2). Several sets of adhesins or receptors are involved in
K Kanai et al.
The Southeast Asian journal of tropical medicine and public health, 28(4), 781-790 (1998-07-10)
Specific binding between bacterial cells and host tissue is an early step of the pathogenesis of infection. Burkholderia pseudomallei cells, the causative micro-organisms of melioidosis, were demonstrated to bind specifically to tissue glycolipids (asialo GM1 and asialo GM2) by solid

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