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G1166

Sigma-Aldrich

Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse

clone GAD-6, purified immunoglobulin, buffered aqueous solution

Synonyme(s) :

Anti-GAD 65

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About This Item

Numéro MDL:
MFCD03455043
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Conjugué

unconjugated

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

GAD-6, monoclonal

Forme

buffered aqueous solution

Espèces réactives

mammals (and some lower vertebrates)

Technique(s)

immunohistochemistry: 1:100-1:500
western blot: 1:1,000-1:5,000

Isotype

IgG2a

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GAD2(2572)
mouse ... Gad2(14417)

Spécificité

Recognizes the lower molecular weight isoform of the two GAD isoforms identified in brain, GAD 65. Can be used for immunochemical localization of GABA secreting neurons.

Immunogène

purified rat brain GAD 65.

Forme physique

Solution in 0.01 M phosphate buffered saline, containing 0.04% sodium azide.

Notes préparatoires

Purified using Protein A chromatography.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Stathis S Leondopulos et al.
Journal of neural engineering, 9(2), 026015-026015 (2012-03-01)
Slow wave oscillations in the brain are essential for coordinated network activity but have not been shown to self-organize in vitro. Here, the development of dissociated hippocampal neurons into an active network with oscillations on multi-electrode arrays was evaluated in
Han-Byeol Kim et al.
Cell death discovery, 6, 73-73 (2020-08-21)
Neonatal maternal separation (NMS), as an early-life stress (ELS), is a risk factor to develop emotional disorders. However, the exact mechanisms remain to be defined. In the present study, we investigated the mechanisms involved in developing emotional disorders caused by
H Hu et al.
Neuroscience, 227, 211-222 (2012-10-09)
Cannabinoid 1 receptors (CB(1)) are highly expressed on presynaptic terminals in the brain where they are importantly involved in the control of neurotransmitter release. Alteration of CB(1) expression is associated with a variety of neurological and psychiatric disorders. There is
Azadeh Yazdan-Shahmorad et al.
eLife, 7 (2018-05-29)
Brain stimulation modulates the excitability of neural circuits and drives neuroplasticity. While the local effects of stimulation have been an active area of investigation, the effects on large-scale networks remain largely unexplored. We studied stimulation-induced changes in network dynamics in
Rossella De Cegli et al.
Nucleic acids research, 41(2), 711-726 (2012-11-28)
Gene expression profiles can be used to infer previously unknown transcriptional regulatory interaction among thousands of genes, via systems biology 'reverse engineering' approaches. We 'reverse engineered' an embryonic stem (ES)-specific transcriptional network from 171 gene expression profiles, measured in ES
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