F1305

Anti-FEN-1 (C-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-Flap endonuclease, Anti-Flap structure-specific endonuclease 1
• Numéro MDL: MFCD09039190
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 45 kDa
• Espèces réactives: human
• Concentration: ~1 mg/mL
• Technique(s): immunoprecipitation (IP): 2-4 μg using HEK 293T cell lysates; indirect immunofluorescence: 5-10 μg/mL using paraformaldehyde-fixed HEK 293T cells; western blot: 0.5-1 μg/mL using K562 cell lysates
• Numéro d'accès UniProt: P39748
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Informations sur le gène: human ... FEN1(2237) ; mouse ... Fen1(14156) ; rat ... Fen1(84490)

Description

Immunogène

synthetic peptide corresponding to amino acids 367-380 of human FEN-1, conjugated to KLH via an N-terminal added cysteine residue. The corresponding sequence in rat and mouse differs by one and two amino acids, respectively.

Description de la cible

FEN-1 (C-terminal) encodes a protein that removes 5′ overhanging flaps in DNA repair and processes the 5′ ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch b

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)