D1814

Anti-DcR3 antibody produced in rabbit

~0.5 mg/mL, IgG fraction of antiserum, buffered aqueous solution

• Synonyme(s) : Anti-Decoy Receptor 3, Anti-TNFRSF6B, Anti-TR6
• Numéro MDL: MFCD02686088
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: IgG fraction of antiserum
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 33 kDa
• Espèces réactives: mouse, rat, human
• Concentration: ~0.5 mg/mL
• Technique(s): microarray: suitable; western blot: 1:500-1:1,000 using human heart, brain or kidney lysates
• Numéro d'accès UniProt: O95407
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TNFRSF6B(8771) ; mouse ... Dcr3(497118)

Description

Description générale

It is a member of the tumor necrosis factor receptor superfamily (TR6). DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Immunogène

synthetic peptide corresponding to amino acids 31-46 of human DcR3 precursor.

Application

Anti-DcR3 antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1000 using human heart, brain or kidney lysates.

Actions biochimiques/physiologiques

DcR3 is a soluble decoy receptor that binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis.

Forme physique

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.