AV32195

Anti-DBP (AB2) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-D site of albumin promoter (albumin D-box) binding protein
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 34 kDa
• Espèces réactives: human
• Concentration: 0.5 mg - 1 mg/mL
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès NCBI: NP_001343
• Numéro d'accès UniProt: Q10586
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... DBP(1628)

Description

Description générale

Albumin promoter (albumin D-box) D-site binding protein (DBP), a PAR basic region leucine zipper (bZIP) protein, is a transcription factor involved in the diurnal regulation of gene transcription in the brain, liver and kidney. It regulates the expression of proteins such as cholesterol 7 α-hydroxylase P450 gene (CYP7) and kisspeptins (Kiss1).

DBP is known to control the growth of liver cells.

Rabbit polyclonal anti-DBP reacts with bovine, canine, human, mouse, and rat D-site of albumin promoter (albumin D-box) binding proteins.

Immunogène

Synthetic peptide directed towards the N terminal region of human DBP

Application

Rabbit Anti-DBP can be used for western blot applications at a concentration of 0.5-5.0μg/ml. It can also be used for immunohistochemistry at 4-8μg/ml, using paraffin-embedded tissues.

Rabbit polyclonal anti-DBP is used to tag D site of albumin promoter (albumin D-box) binding protein for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of D site of albumin promoter (albumin D-box) binding protein in diurnal regulation of gene expression.

Actions biochimiques/physiologiques

D-site-binding protein (DBP) is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family.

Séquence

Synthetic peptide located within the following region: PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGR

Forme physique

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable