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Y0000683

Phenylephrine hydrochloride for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(R)-(−)-Phenylephrine hydrochloride, (R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride

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About This Item

Formule linéaire :
HOC6H4CH(CH2NHCH3)OH·HCl
Numéro CAS:
61-76-7
Poids moléculaire :
203.67
Numéro Beilstein :
4158948
Numéro MDL:
MFCD00012605
Code UNSPSC :
41116107
ID de substance PubChem :
329831094
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

phenylephrine

Fabricant/nom de marque

EDQM

Pf

143-145 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

OC1=CC([C@H](CNC)O)=CC=C1.Cl

InChI

1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

Clé InChI

OCYSGIYOVXAGKQ-FVGYRXGTSA-N

Informations sur le gène

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenylephrine hydrochloride for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

PHR1017

Phenylephrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

P1240000

Phenylephrine, European Pharmacopoeia (EP) Reference Standard

P1250000

Phenylephrine hydrochloride, European Pharmacopoeia (EP) Reference Standard

1533002

Phenylephrine hydrochloride, United States Pharmacopeia (USP) Reference Standard

PHR1695

Phenylephrine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1712

Phenylephrine Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

1533046

Phenylephrine Related Compound E, United States Pharmacopeia (USP) Reference Standard

1533035

Phenylephrine Related Compound D, United States Pharmacopeia (USP) Reference Standard

1532950

Phenylephrine bitartrate, United States Pharmacopeia (USP) Reference Standard

1533024

Phenylephrine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1533261

Phenylephrine Related Compound F, United States Pharmacopeia (USP) Reference Standard

1533272

Phenylephrine Related Compound G, United States Pharmacopeia (USP) Reference Standard

BP284

Phenylephrine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2153

2-Hydroxy-N-[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]-N-methylacetamide, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2151

1,2,3,4-Tetrahydro-4,6-dihydroxy-2-methylisoquinoline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2148

Phenylephrine Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2154

N-Formylphenylephrine, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2149

Phenylephrine Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2150

Phenylephrine Related Compound G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3221

Phenylephrine Bitartrate, pharmaceutical secondary standard, certified reference material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H317

Classification des risques

Acute Tox. 4 Oral - Skin Sens. 1B

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Y0001170

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Paracetamol impurity J European Pharmacopoeia (EP) Reference Standard

Y0001945

Paracetamol impurity J

4-Aminophénol European Pharmacopoeia (EP) Reference Standard

Y0001955

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Méthylparaben Pharmaceutical Secondary Standard; Certified Reference Material

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Edmund Tsui et al.
Experimental eye research, 112, 134-138 (2013-05-25)
The impact of mydriatic agents on the standardized provocation of retinal vascular reactivity has not been systematically investigated. Our aim was to investigate the effect of commonly used mydriatic agents on the provoked vascular response of retinal arterioles. One eye
Thomas R Sundermeier et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(8), 3780-3791 (2014-05-09)
Photoreceptor cell death is the proximal cause of blindness in many retinal degenerative disorders; hence, understanding the gene regulatory networks that promote photoreceptor survival is at the forefront of efforts to combat blindness. Down-regulation of the microRNA (miRNA)-processing enzyme DICER1
Shigehiko Ogoh et al.
Anesthesia and analgesia, 118(4), 823-829 (2014-03-22)
Spatially resolved near-infrared spectroscopy-determined frontal lobe tissue oxygenation (ScO2) is reduced with administration of phenylephrine, while cerebral blood flow may remain unaffected. We hypothesized that extracranial vasoconstriction explains the effect of phenylephrine on ScO2. We measured ScO2 and internal and
B L Sng et al.
Anaesthesia, 69(1), 37-45 (2013-11-22)
Hypotension necessitating vasopressor administration occurs commonly during caesarean section under spinal anaesthesia. We developed a novel vasopressor delivery system that automatically administers phenylephrine or ephedrine based on continuous non-invasive arterial pressure monitoring. A phenylephrine bolus of 50 μg was given
Dale A Currigan et al.
Anesthesiology, 121(5), 930-936 (2014-09-10)
Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right
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