PHR1578

Triéthanolamine

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : 2,2′,2′′-nitrilotriéthanol, Tris(2-hydroxyéthyl)amine
• Formule linéaire : (HOCH₂CH₂)₃N
• Numéro CAS: 102-71-6
• Poids moléculaire : 149.19
• Beilstein: 1699263
• Numéro CE : 203-049-8
• Numéro MDL: MFCD00002855
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823486
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to Ph. Eur. T2545000; traceable to USP 1696958
• Densité de vapeur: 5.14 (vs air)
• Pression de vapeur: 0.01 mmHg ( 20 °C)
• Famille d'API: trolamine
• CofA (certificat d'analyse): current certificate can be downloaded
• Température d'inflammation spontanée: 600 °F
• Limite d'explosivité: 8.5 %
• Conditionnement: ampule of 5 mL
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Indice de réfraction: n20/D 1.485 (lit.)
• Plage de pH utile: 7.3-8.3
• pKa (25 °C): 7.8
• pb: 190-193 °C/5 mmHg (lit.)
• Pf: 17.9-21 °C (lit.)
• Densité: 1.124 g/mL at 25 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: OCCN(CCO)CCO
• InChI: 1S/C6H15NO3/c8-4-1-7(2-5-9)3-6-10/h8-10H,1-6H2
• Clé InChI: GSEJCLTVZPLZKY-UHFFFAOYSA-N

Description

Description générale

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standard. Trolamine belongs to the family of ethanolamines, offering a broad spectrum of applications due to its ability to combine the properties of both amines and alcohols.[1] Its property as an organic base to form soluble neutralization products with insoluble acids is reported.[2]

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC2885 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 354.2 °F - closed cup
• Point d'éclair (°C): 179 °C - closed cup