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72706

Sigma-Aldrich

L-Leucine

tested according to Ph. Eur.

Synonyme(s) :

Leucinum, (S)-2-Amino-4-methylpentanoic acid

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About This Item

Formule linéaire :
(CH3)2CHCH2CH(NH2)CO2H
Numéro CAS:
Poids moléculaire :
131.17
Numéro Beilstein :
1721722
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352209
ID de substance PubChem :

Agence

USP/NF
tested according to Ph. Eur.

Pureté

98.5-101.0%

Forme

powder

Couleur

white

Pf

>300 °C (lit.)

Chaîne SMILES 

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

Clé InChI

ROHFNLRQFUQHCH-YFKPBYRVSA-N

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Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Sebastian Kalamajski et al.
Matrix biology : journal of the International Society for Matrix Biology, 29(4), 248-253 (2010-01-19)
Small leucine-rich proteoglycans/proteins (SLRPs) are associated with collagen fibril formation, and therefore important for the proper formation of extracellular matrices. SLRPs are differentially expressed in tissues and during pathological conditions, contributing to the development of connective tissue properties. The binding
Qian Wang et al.
Journal of the National Cancer Institute, 105(19), 1463-1473 (2013-09-21)
L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling and protein synthesis. LAT1 and LAT3 are overexpressed at different stages of prostate cancer, and they are responsible for
M Sakamoto et al.
The Journal of clinical endocrinology and metabolism, 56(1), 202-204 (1983-01-01)
Recent studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin from bovine adrenal medulla and human pheochromocytoma have revealed that this precursor molecule contains four copies of methionine-enkephalin (Met-Enk) and one copy each of leucine-enkephalin (Leu-Enk)
T Yoshimasa et al.
The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with
Luc J C van Loon
Current opinion in clinical nutrition and metabolic care, 15(1), 71-77 (2011-11-01)
Amino acids do not merely represent precursors for de-novo protein synthesis, but also function as nutritional signals regulating various metabolic processes. In fact, ample evidence has been generated to show that various tissues respond to changes in amino acid availability

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