37019

Atropine

analytical standard

• Synonyme(s) : Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
• Formule empirique (notation de Hill) : C₁₇H₂₃NO₃
• Numéro CAS: 51-55-8
• Poids moléculaire : 289.37
• Beilstein: 91260
• Numéro CE : 200-104-8
• Numéro MDL: MFCD00022622
• Code UNSPSC : 85151701
• ID de substance PubChem : 329755584
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): cleaning products; cosmetics; food and beverages; personal care
• Format: neat
• Température de stockage: −20°C
• Chaîne SMILES: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
• Clé InChI: RKUNBYITZUJHSG-SPUOUPEWSA-N
• Informations sur le gène: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Description

Description générale

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.[1]

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.[1]
For the analysis of the phytotoxins.

Application

Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).[2]
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.[3]
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.[4]
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.[5]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).[2]
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.[3]
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.[4]
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.[5]

Actions biochimiques/physiologiques

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Reconstitution

Dried down, ~100μg/mL after reconstitution with 1 mL of water

Remarque sur l'analyse

purity : ≥96.0% (HPLC)

Informations légales

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H330
• Conseils de prudence: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Classification des risques: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable