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34001

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Ceftiofur

VETRANAL®, analytical standard

Synonyme(s) :

3-[(2-Furylcarbonyl)thio]methyl]-7-[2-(2-amino-4-thiazolyl)-2-(methoxyiminoacetamido)-3-cephem-4-carboxylic acid

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About This Item

Formule empirique (notation de Hill):
C19H17N5O7S3
Numéro CAS:
80370-57-6
Poids moléculaire :
523.56
Numéro MDL:
MFCD00864953
Code UNSPSC :
41116107
ID de substance PubChem :
329754745
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

CO\N=C(/C(=O)N[C@H]1C2SCC(CSC(=O)c3ccco3)=C(N2C1=O)C(O)=O)c4csc(N)n4

InChI

1S/C19H17N5O7S3/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28)/b23-11-/t12-,16?/m1/s1

Clé InChI

ZBHXIWJRIFEVQY-FITYNHDMSA-N

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Catégories apparentées

Description générale

Ceftiofur is a third-generation cephalosporin antibiotic, which is commonly used in veterinary medicine for the treatment of respiratory diseases and bacterial infections in farm animals.

Application

Ceftiofur has been used as an analytical reference standard for the determination of the analyte in:
  • Milk samples using receptor binding assays such as Betastar Combo, SNAP, and Twinsensor tests.
  • Environmental water samples using capillary electrophoresis.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H317,H334

Classification des risques

Resp. Sens. 1 - Skin Sens. 1

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCK8841
BCCD2522
BCBS8768V
BCBS8758V
SZBF222XV

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Improving the sensitivity of the determination of ceftiofur by capillary electrophoresis in environmental water samples: In-line solid phase extraction and sample stacking techniques.
Puig P, et al.
Analytica Chimica Acta, 587(2), 208-215 (2007)
Rex E Hornish et al.
Current topics in medicinal chemistry, 2(7), 717-731 (2002-06-08)
Cephalosporins are an important class of antibacterial agents in use today for both humans and animals. Four generations of cephalosporins have evolved, all of which contain the beta-lactam sub-structure first found in penicillin. The range of cephalosporins available for use
Determination of ceftiofur and its metabolite desfuroylceftiofur in bovine serum and milk by ion-paired liquid chromatography.
Tyczkowska LK, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 614(1), 123-134 (1993)
Tate B Morris et al.
Frontiers in veterinary science, 7, 284-284 (2020-06-26)
The nociceptive blockade of locoregional anesthesia prior to surgical stimulation can decrease anesthetic agent requirement and thereby potential dose-dependent side effects. The use of an ipsilateral second and third cervical spinal nerve locoregional anesthetic block for prosthetic laryngoplasty in the
Sanjie Caol et al.
BMC veterinary research, 13(1), 293-293 (2017-10-01)
Lyme disease in humans is predominantly treated with tetracycline, macrolides or beta lactam antibiotics that have low minimum inhibitory concentrations (MIC) against Borrelia burgdorferi. Horses with Lyme disease may require long-term treatment making frequent intravenous or intramuscular treatment difficult and
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