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MAB338

Sigma-Aldrich

Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68

clone 4-68, Chemicon®, from mouse

Synonyme(s) :

CNTF

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

4-68, monoclonal

Espèces réactives

mouse, rat, human, monkey

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... CNTF(1270)

Spécificité

Ciliary neurotrophic factor. Detects a 22 kD band in Western blots of rat sciatic nerve extract.

Immunogène

Purified ciliary neurotrophic factor from rat sciatic nerve.

Application

Immunohistochemistry: 10-20 μg/mL on frozen sections of rat sciatic nerve perfused and counter-fixed with 4% paraformaldehyde (Stockli et al., 1991).

Western blotting: 10 μg/mL (Stockli et al., 1991)

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
This Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68 is validated for use in WB, IH for the detection of Ciliary Neurotrophic Factor.

Forme physique

Format: Purified
Liquid in 0.02M phosphate buffer, 0.25M NaCl with 0.1% sodium azide, pH 7.6.

Stockage et stabilité

Maintain at 2-8°C for up to 6 months. Avoid repeated freeze/thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Cuihong Jia et al.
Glia, 66(11), 2456-2469 (2018-12-01)
Astrocyte-derived ciliary neurotrophic factor (CNTF) promotes adult subventricular zone (SVZ) neurogenesis. We found that focal adhesion kinase (FAK) and JNK, but not ERK or P38, repress CNTF in vitro. Here, we defined the FAK-JNK pathway and its regulation of CNTF
Cuihong Jia et al.
Stem cell research, 49, 102061-102061 (2020-11-02)
Constant neuroregeneration in adult olfactory epithelium maintains olfactory function by basal stem cell proliferation and differentiation to replace lost olfactory sensory neurons (OSNs). Understanding the mechanisms regulating this process could reveal potential therapeutic targets for stimulating adult olfactory neurogenesis under
Milena Girotti et al.
Neuropharmacology, 160, 107791-107791 (2019-09-26)
Deficits in cognitive flexibility, i.e. the ability to modify behavior in response to changes in the environment, are present in several psychiatric disorders and are often refractory to treatment. However, improving treatment response has been hindered by a lack of
Anna Polosa et al.
International journal of molecular sciences, 20(11) (2019-06-07)
To unravel the mechanisms behind the higher resistance to light damage of juvenile (JR) versus adult (AR) rats, Sprague Dawley rats were exposed to a bright luminous environment of 10, 000 lux. The light-induced retinopathy (LIR) was assessed with histology
Laurène Cagnon et al.
Neurobiology of disease, 33(1), 133-142 (2008-11-11)
In pediatric patients, hyperammonemia can provoke irreversible damages to developing CNS like cortical atrophy, ventricular enlargement, demyelination or gray and white matter hypodensities which are concordant with alterations of neurons and oligodendrocytes. Cerebral injury triggers endogenous protective mechanisms that can

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