ABF207

Anti-TIRP Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : TIR domain-containing adapter molecule 2, TICAM-2, Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: rat, human, mouse
• Technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès UniProt: Q86XR7
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... TICAM2(353376)

Description

Description générale

Toll/interleukin-1 receptor domain-containing protein (TIRP), also known as TIR domain-containing adapter molecule 2 (TICAM2), also known as Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule (TRAM), and Toll-like receptor adaptor protein 3 (TIRAP3), is an adaptor protein containing one TIR domain, and is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) serving as an important link between the innate and adaptive immune responses. TIRP is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas.

Spécificité

This antibody recognizes the C-terminus of TIRP.

Immunogène

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human TIRP.

Application

Detect Toll/interleukin-1 receptor domain-containing protein using this rabbit polyclonal antibody, Anti-TIRP Antibody validated for use in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected TIRP in mouse kidney tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected TIRP in mouse kidney cells.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualité

Evaluated by Western Blotting in human, mouse, and rat kidney tissue lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected TIRP in human, mouse, and rat kidney tissue lysates.

Description de la cible

~26 kDa observed. Uncharacterized bands may appear in some lysates.

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human, mouse, and rat kidney tissue lysates

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable