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481981

Nifedipine

Name: Nifedipine
Brand: MM
Price: 71.6 EUR
Availability: InStock

≥98% (UV), L-type Ca2+ channel bocker, solid

Synonyme(s) :

Nifedipine, L-Type Calcium Channel Blocker III

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À vous/Référence	Disponibilité	Prix
250 mg	Date d'expédition estimée le01 juin 2026DeMerck Life Science BV/SRL	71,60 €

A propos de cet article

Formule empirique (notation de Hill) :

C₁₇H₁₈N₂O₆

Numéro CAS:

21829-25-4

Poids moléculaire :

346.33

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00057326

Assay:

≥98% (UV)

Form:

solid

Storage condition:

OK to freeze, protect from light

71,60 €

Date d'expédition estimée le01 juin 2026Détails

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Propriétés

Nom du produit

Nifedipine, Relatively selective blocker of L-type Ca²⁺ channels.

description

Merck USA index - 14, 6528

Quality Segment

100

assay

≥98% (UV)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

yellow

solubility

DMSO: soluble, ethanol: soluble

shipped in

ambient

storage temp.

10-30°C

SMILES string

[N+](=O)([O-])c1c(cccc1)C2C(=C(NC(=C2C(=O)OC)C)C)C(=O)OC

InChI

1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3

InChI key

HYIMSNHJOBLJNT-UHFFFAOYSA-N

Description

General description

Relatively selective blocker of L-type Ca²⁺ channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca²⁺ channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells.

Biochem/physiol Actions

Product does not compete with ATP.

Reversible: no

Cell permeable: no

Primary Target
L-type Ca2+ channels

Preparation Note

Following reconstitution, refrigerate (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Reid, K., et al. 1997. J. Pharmacol. Exp. Ther. 283, 993.
Kondo, S., et al. 1995. J. Neurosurg.82, 469.
Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9.
Calabresi, P., et al. 1994. J. Neurosci. 14, 4871.
Akman, M.S., et al. 1993. Endocrinology132, 1286.
Cirillo, M., et al. 1993. Circ. Res.72, 847.
Young, R.J., et al. 1993. Biochim. Biophys. Acta1146, 81.
Janis, R., et al. 1987. Adv. Drug Res.16, 311.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

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1 of 1

Cet article	PHR1290	N0750000	BP462
Sigma-Aldrich 481981 Nifedipine	Supelco PHR1290 Nifedipine	N0750000 Nifedipine	BP462 Nifedipine
assay ≥98% (UV)	assay -	assay -	assay -
form solid	form -	form -	form solid
Quality Level 100	Quality Level 300	Quality Level -	Quality Level -
manufacturer/tradename Calbiochem^®	manufacturer/tradename -	manufacturer/tradename EDQM	manufacturer/tradename BP
storage temp. 10-30°C	storage temp. 2-30°C	storage temp. -	storage temp. 2-8°C
storage condition OK to freeze, protect from light	storage condition -	storage condition -	storage condition -

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c