QBD10722

Hydroxy-dPEG^®₂₄-t-butyl ester

>90% (HPLC)

• Synonyme(s) : HO-PEG₂₄-CO-Otbu, HO-PEG₂₄-TBE, Hydroxy-PEG-t-butyl ester, Hydroxy-PEG₂₄-t-butyl-ester, PEG₁₀₀₀-t-butyl ester
• Formule empirique (notation de Hill): C₅₅H₁₁₀O₂₇
• Poids moléculaire : 1203.45
• Numéro MDL: MFCD13185018
• Code UNSPSC : 12352108
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: >90% (HPLC)
• Forme: solid or viscous liquid
• Capacité de réaction: reaction type: Pegylations
• Architecture des polymères: shape: linear; functionality: heterobifunctional
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Caractéristiques et avantages

Hydroxy-dPEG₂₄-t-butyl ester is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain, comparable to a polymeric PEG₁₀₀₀. The single molecular weight, discrete-length PEG (dPEG) chain is 86 atoms (88.5 Å) long. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. The tert-butyl ester deprotects with trifluoroacetic acid (TFA), exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Informations légales

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable