QBD10289

m-dPEG^®₁₂-MAL

• Synonyme(s) : Polyethylene glycol
• Formule empirique (notation de Hill): C₃₂H₅₈N₂O₁₅
• Numéro CAS: 88504-24-9
• Poids moléculaire : 710.81
• Numéro MDL: MFCD11041152
• Code UNSPSC : 51171641
• ID de substance PubChem : 329823909
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: >90%
• Forme: solid or viscous liquid
• Pertinence de la réaction: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: sulfhydryl reactive; reagent type: linker; reactivity: thiol reactive
• Architecture des polymères: shape: linear; functionality: monofunctional
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O

Description

Caractéristiques et avantages

The m-dPEG^®₁₂-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₁₂-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Informations légales

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable