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905046

Sigma-Aldrich

Conjugated Polymer Nanoparticles incorporating iron oxide

fluorescence λem 550 nm, 100 μg/mL in H2O

Synonyme(s) :

Conjugated polymer nanoparticles, Fluorescent magnetic nanoparticles, Fluorescent nanoparticles, Magneto-conjugated polymer nanoparticles

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About This Item

Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Forme

nanoparticles

Concentration

100 μg/mL in H2O

Fluorescence

λem 550 nm

Température de stockage

2-8°C

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Application

Iron oxide containing conjugated polymer nanoparticles are water-soluble nanoparticles compromising of light-emitting polymer and iron oxide. The presence of iron oxide in core makes these fluorescent nanoparticles distinctly different than conventional dyes as it allows their manipulation with a magnetic field. These nanoparticles possess a ′core-shell′ structure where light-emitting polymer and iron oxide are encapsulated in biocompatible surfactant.
The ′core-shell′ structure consisting of polymer and iron oxide in the core and the biocompatible surfactant in the surrounding shell allows easy covalently bonding of these nanoparticles with biomolecules such streptavidin, antibodies, proteins, nucleic acids, etc and make them suitable for the following applications:
  • Fluorescence Microscopy (high content screening, live cell tracking and 3-D cell imaging)
  • Immunohistochemistry and Immunocytochemistry
  • Flow Cytometry
  • Rapid Diagnostic Tests (RDTs)
  • Tissue Imaging
  • 2-Photon Imaging
  • NIR Imaging

Stockage et stabilité

The robustness of CPNs enables them to be used under high intensity illumination and in extreme experimental conditions if required, while their 24-month shelf-life permits convenient storage at ambient temperatures.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Magnetic conjugated polymer nanoparticles as bimodal imaging agents.
Howes P, Green M, Bowers A, et al.
Journal of the American Chemical Society, 132(28), 9833-9842 (2010)
General synthesis of high-performing magneto-conjugated polymer core?shell nanoparticles for multifunctional theranostics
H Yan et al.
Nano Research, 10, 704-704 (2017)
General synthesis of high-performing magneto-conjugated polymer core-shell nanoparticles for multifunctional theranostics
Yan H, et al.
Nano Research, 10(2), 704-717 (2017)
Loading Graphene Quantum Dots into Optical-Magneto Nanoparticles for Real-Time Tracking In Vivo
Wang Y, et al.
Materials, 12(13), 2191-2191 (2019)
Fluorescent magnetic nanoparticles for biomedical applications
Chekina N, et al.
Journal of Materials Chemistry, 21(21), 7630-7639 (2011)

Articles

Iron oxide incorporated CPNs offer high brightness for fluorescence and MRI applications, encapsulated in biocompatible surfactant.

CPNs offer sensitivity and stability, aiding various assays; may enable rapid diagnostic tests for healthcare needs.

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