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329967
(+)-Usnic acid
98%
Synonyme(s) :
(+)-Usnic acid from Usnea dasypoga, 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3(2H,9bH)-dione
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5 G
81,90 €
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104,00 €
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5 G
81,90 €
25 G
104,00 €
About This Item
Formule empirique (notation de Hill) :
C18H16O7
Numéro CAS:
Poids moléculaire :
344.32
Beilstein:
96698
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352106
ID de substance PubChem :
Nomenclature NACRES :
NA.22
81,90 €
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Niveau de qualité
Essai
98%
Forme
powder
Activité optique
[α]25/D +488°, c = 0.7% in chloroform
Pf
201-203 °C (lit.)
Groupe fonctionnel
ketone
Chaîne SMILES
C[C@](C1=C(O)C(C)=C(O)C(C(C)=O)=C1O2)(C(C3C(C)=O)=O)C2=CC3=O
InChI
1S/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5,22-24H,1-4H3/t18-/m1/s1
Clé InChI
ICTZCAHDGHPRQR-GOSISDBHSA-N
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Catégories apparentées
Description générale
(+)-Usnic acid is a bioactive compound mainly found as a secondary metabolite in lichens.[1]
Application
(+)-Usnic acid has been used to study the following:
- The mechanism of its antimicrobial activity in bacterial cells.[2]
- Its ability as an antibiofilm agent against Group A Streptococci (GAS).[1]
- Its ability as a potent anti-virulent compound against Candida albicans.[3]
- The mechanism of its toxic effect on hepatocytes.[4]
- Its ability to inhibit the motility of human lung cancer cells.[5]
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Acute Tox. 4 Oral
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
dust mask type N95 (US), Eyeshields, Gloves
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Les clients ont également consulté
Michal Goga et al.
Ecology and evolution, 8(5), 2781-2787 (2018-03-14)
Lichens and mosses often share the same environmental conditions where they compete for substrate and other essential factors. Lichens use secondary metabolites as allelochemicals to repel surrounding plants and potential rivals. In mosses, endoreduplication leads to the occurrence of various
Kunal Kumar et al.
Chemico-biological interactions, 315, 108898-108898 (2019-11-13)
Usnic acid, a dibenzofuran derivative found in many lichen species, is reported to have anticancer activity against human gastric cancer. We investigated the molecular alterations associated with anticancer effects of usnic acid against human gastric adenocarcinoma AGS and gastric carcinoma
Sohaila Erfani et al.
Iranian journal of basic medical sciences, 23(9), 1225-1231 (2020-09-24)
Cerebral ischemia/reperfusion causes complex pathological mechanisms that lead to brain tissue damage. Usnic acid is a lichen secondary metabolite that has many different biological properties including anti-inflammatory and anti-oxidant activities. Therefore, the objective of the current study was to investigate
Inhibitory Activity of (+)-Usnic Acid against Non-Small Cell Lung Cancer Cell Motility.
Yang Y, et al.
PLoS ONE, 11(1), e0146575-e0146575 (2016)
Usnic acid inhibits biofilm formation and virulent morphological traits of Candida albicans.
Nithyanand P, et al.
Microbiological research, 179, 20-28 (2015)
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Do you offer any interpretation of the IR spectrum of Product 329967, (+)-Usnic acid?
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Although we do not perform any detailed analysis of IR spectrum as part of our routine QC testing for this product, we can say that the broad stretch around 3000 cm-1is due to hydrogen-bonded hydroxyl (OH) groups and the band at 1700 cm-1 is due to the carbonyl (C=O).
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