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11715

Sigma-Aldrich

Sodium barbiturate

≥97.0% (T)

Synonyme(s) :

Barbituric acid sodium salt

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About This Item

Formule empirique (notation de Hill) :
C4H3N2NaO3
Numéro CAS:
Poids moléculaire :
150.07
Beilstein:
3748030
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22

110,00 €


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Essai

≥97.0% (T)

Solubilité

hot water: soluble 0.2 g/10 mL, clear, colorless

Chaîne SMILES 

[Na+].[O-]C1=NC(=O)NC(=O)C1

InChI

1S/C4H4N2O3.Na/c7-2-1-3(8)6-4(9)5-2;/h1H2,(H2,5,6,7,8,9);/q;+1/p-1

Clé InChI

MHQHHBYRYFICDV-UHFFFAOYSA-M

Description générale

Sodium barbiturate is a white to light beige powder. It accelerates the propagation of metastatic prostate adenocarcinomas in rats and in tissue culture[1].

Application

Sodium barbiturate has been used for quantification of thrombin in plasma[2]. It has been used in the estimation of trypsin in duodenal contents[3]. It was also used as a buffer to characterise the functions of two long-chain fatty acid CoA ligase genes (facl) in crude oil-degrading Geobacillus thermodenitrificans NG80-2[4].

Autres remarques

Sales restrictions may apply

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

F A Ofosu et al.
Blood, 64(3), 742-747 (1984-09-01)
Heparan with a low affinity for antithrombin III has previously been demonstrated to inhibit thrombin generation in both normal plasma and plasma depleted of antithrombin III. In addition, standard heparin and heparin with a low affinity for antithrombin III have
Simple method for estimating trypsin.
H S Wiggins
Gut, 8(4), 415-416 (1967-08-01)
M Pollard et al.
Oncology, 34(3), 129-132 (1977-01-01)
Metastatic prostate adenocarcinomas, derived from aging germfree Wistar rats, have been propagated in rats and in tissue culture. A protocol has been developed and demonstrated for assay of treatments which retard or which accelerate the rate and extent of tumor
Vadivel Parthsarathy et al.
PloS one, 8(1), e54769-e54769 (2013-02-06)
Previously, we have developed a retro-inverso peptide inhibitor (RI-OR2, rGffvlkGr) that blocks the in vitro formation and toxicity of the Aβ oligomers which are thought to be a cause of neurodegeneration and memory loss in Alzheimer's disease. We have now
Szilvia Hajdok et al.
The Journal of organic chemistry, 74(19), 7230-7237 (2009-09-11)
The laccase-catalyzed reaction between catechols and heterocyclic 1,3-dicarbonyls (pyridinones, quinolinones, thiocoumarins) using aerial oxygen as the oxidant delivers benzofuropyridinones, benzofuroquinolinones, and thiocoumestans in a simple fashion, highly regioselectively with yields ranging from 55 to 98%. With barbituric acid derivatives the

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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