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Merck

PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

Synonymes:
PRKAR1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5575) Summary: Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM, Jun 2009]
  • Mouse(19085) protein kinase, cAMP dependent regulatory, type I beta
  • Rat(25521) protein kinase, cAMP dependent regulatory, type I, beta
  • Zebrafish(767685) protein kinase, cAMP-dependent, regulatory, type I, beta
  • Horse(100054262) protein kinase, cAMP-dependent, regulatory, type I, beta
  • cow(505370) protein kinase, cAMP-dependent, regulatory, type I, beta
  • dog(480805) protein kinase, cAMP-dependent, regulatory, type I, beta
  • domestic cat(101085259) protein kinase, cAMP-dependent, regulatory, type I, beta
  • chicken(416446) protein kinase, cAMP-dependent, regulatory, type I, beta
  • domestic guinea pig(100713839) protein kinase, cAMP-dependent, regulatory, type I, beta
  • naked mole-rat(101700715) protein kinase, cAMP-dependent, regulatory, type I, beta

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PRKAR1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-PRKAR1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
H-89 dihydrochloride hydrate, ≥98% (HPLC), powder,
Espèce(s)
human
8-(4-Chlorophenylthio)adenosine 3′,5′-cyclic monophosphate sodium salt, ≥97.0% (HPLC), powder,
Espèce(s)
human
Propentofylline, solid,
Espèce(s)
human
3-Isobutyl-1-méthylxanthine, ≥99% (HPLC), powder,
Espèce(s)
rat, human
H-8 dihydrochloride, >98% (HPLC),
Espèce(s)
human, rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PRKAR1B,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Prkar1b,
Espèce(s)
mouse