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Merck

NTRK2

neurotrophic tyrosine kinase, receptor, type 2

Synonymes:
GP145-TrkB, TRKB, trk-B
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4915) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18212) neurotrophic tyrosine kinase, receptor, type 2
  • Rat(25054) neurotrophic tyrosine kinase, receptor, type 2
  • domestic cat(101101347) neurotrophic tyrosine kinase, receptor, type 2
  • naked mole-rat(101720037) neurotrophic tyrosine kinase, receptor, type 2
  • dog(484147) neurotrophic tyrosine kinase, receptor, type 2
  • Domestic Rabbit(100352548) neurotrophic tyrosine kinase, receptor, type 2
  • domestic guinea pig(100723565) neurotrophic tyrosine kinase, receptor, type 2
  • chicken(396157) neurotrophic tyrosine kinase, receptor, type 2
  • cow(505824) neurotrophic tyrosine kinase, receptor, type 2
  • Horse(100061700) neurotrophic tyrosine kinase, receptor, type 2
  • sheep(101116015) neurotrophic tyrosine kinase, receptor, type 2

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Phosphotyrosine NTRK2 / BDNF/NT-3 Growth Factors Receptor ELISA Kit, ,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-phospho-TrkB (Tyr816) Antibody, clone 2C21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, human, mouse, rat, sheep
Application
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anticorps anti-TrkB, serum, Chemicon®,
Espèces réactives
mouse, rat
Application
immunohistochemistry
Anti-phospho-Trk B (pTyr515) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-TrkB antibody produced in goat, affinity isolated antibody, lyophilized powder,
Espèces réactives
human
Application
flow cytometry
western blot
Anti-Trk-B Antibody, clone 2B22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Proteins

Numéro du produit
Description
Espèce(s)
TrkB Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6 tagged, recombinant, human TrkB, amino acids 455-end, for use in Kinase Assays.,
Espèce(s)
human
TrkB/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espèce(s)
human
TRKB (455-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human NTRK2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ntrk2,
Espèce(s)
mouse
MISSION® esiRNA, targeting mouse Ntrk2,
Espèce(s)
mouse