GRIA4
glutamate receptor, ionotropic, AMPA 4
Synonymes:
GLUR4, GLUR4C, GLURD, GluA4
Espèce(s):
Human GRIA4 (2893), Mouse Gria4 (14802), Rat Gria4 (29629), sheep GRIA4 (443274), domestic cat GRIA4 (101087003), chicken GRIA4 (396137), domestic guinea pig Gria4 (100728256), cow GRIA4 (529904), Horse GRIA4 (100061561), dog GRIA4 (489427)
ID UniProtKB:
ID du gène:
- Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
- Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
- Rat(29629) glutamate receptor, ionotropic, AMPA 4
- sheep(443274) glutamate receptor, ionotropic, AMPA 4
- domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
- chicken(396137) glutamate receptor, ionotropic, AMPA 4
- domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
- cow(529904) glutamate receptor, ionotrophic, AMPA 4
- Horse(100061561) glutamate receptor, ionotropic, AMPA 4
- dog(489427) glutamate receptor, ionotropic, AMPA 4
- naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide, ≥98% (HPLC), solid,
Espèce(s)
human
Small Molecule - Allosteric Modulator
Référence du produit
Description
Espèce(s)
Small Molecule - Antagonist
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anticorps anti-récepteur 4 du glutamate, Chemicon®, from rabbit,
Espèces réactives
mouse, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Gria4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-GluR4/GluA4/GRIA4 Antibody, clone 4M5D0, Rabbit Monoclonal, ,
Espèces réactives
mouse, rat
Application
western blot
Anti-GLUR4 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-GRIA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Référence du produit
Description
Espèce(s)
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Small Molecule - Mixed Agonist/Antagonist
Référence du produit
Description
Espèce(s)
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human