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Merck

GPT

glutamic-pyruvate transaminase (alanine aminotransferase)

Synonymes:
AAT1, ALT1, GPT1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2875) Summary: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
  • Mouse(76282) glutamic pyruvic transaminase, soluble
  • Rat(81670) glutamic-pyruvate transaminase (alanine aminotransferase)
  • Thale Cress(818747) UDP-GlcNAc:dolichol phosphate N-acetylglucosamine-1-phosphate transferase
  • fruit fly(5656924) Glutamate pyruvate transaminase
  • dog(609914) glutamic-pyruvate transaminase (alanine aminotransferase)
  • domestic cat(101097207) glutamic-pyruvate transaminase (alanine aminotransferase)
  • cow(539188) glutamic-pyruvate transaminase (alanine aminotransferase)
  • sheep(101110488) glutamic-pyruvate transaminase (alanine aminotransferase)
  • sheep(100286806) glutamic-pyruvate transaminase (alanine aminotransferase)
  • domestic guinea pig(100716607) glutamic-pyruvate transaminase (alanine aminotransferase)
  • naked mole-rat(101713635) glutamic-pyruvate transaminase (alanine aminotransferase)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ANTI-GPT antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-GPT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GPT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Espèces réactives
human
Application
immunohistochemistry
Anti-GPT (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
bovine, dog, guinea pig, human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-GPT antibody produced in mouse, clone 1F10, ascites fluid,
Espèces réactives
human
Application
ELISA
western blot

Kits

Référence du produit
Description
Espèce(s)
Dosage de l'activité ALAT, sufficient for 100 colorimetric or fluorometric tests,
Espèce(s)
human, mouse, rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GPT,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Gpt,
Espèce(s)
mouse