GDNF
glial cell derived neurotrophic factor
Synonymes:
ATF1, ATF2, HFB1-GDNF, HSCR3
Espèce(s):
Human GDNF (2668), Mouse Gdnf (14573), Rat Gdnf (25453), chicken GDNF (395569), sheep GDNF (101117619), naked mole-rat Gdnf (101700544), domestic cat GDNF (101097871), dog GDNF (489224), domestic guinea pig Gdnf (100717276), cow GDNF (386587)
ID UniProtKB:
ID du gène:
- Human(2668) Summary: This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
- Mouse(14573) glial cell line derived neurotrophic factor
- Rat(25453) glial cell derived neurotrophic factor
- chicken(395569) glial cell derived neurotrophic factor
- sheep(101117619) glial cell derived neurotrophic factor
- naked mole-rat(101700544) glial cell derived neurotrophic factor
- domestic cat(101097871) glial cell derived neurotrophic factor
- dog(489224) glial cell derived neurotrophic factor
- domestic guinea pig(100717276) glial cell derived neurotrophic factor
- cow(386587) glial cell derived neurotrophic factor
- Horse(100067053) glial cell derived neurotrophic factor
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ELISA
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-GDNF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-Glial Cell-derived Neurotrophic Factor (GDNF) antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Espèces réactives
human
Application
neutralization
Anti-GDNF antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-GDNF antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-Glial Derived Neurotrophic Factor Antibody, Chemicon®, from sheep,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
Proteins
Référence du produit
Description
Espèce(s)
Glial Cell Line-derived Neurotrophic Factor human, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE),
Espèce(s)
human
GDNF from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
mouse
GDNF human, recombinant, expressed in E. coli, Animal-component free, ≥98% (SDS-PAGE), ≥98% (HPLC),
Espèce(s)
human
Glial Cell Line-derived Neurotrophic Factor from rat, recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE),
Espèce(s)
rat
GDNF from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
rat
esiRNA
Référence du produit
Description
Espèce(s)