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Merck

CYP2E1

cytochrome P450, family 2, subfamily E, polypeptide 1

Synonymes:
CPE1, CYP2E, P450-J, P450C2E
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1571) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008]
  • Mouse(13106) cytochrome P450, family 2, subfamily e, polypeptide 1
  • Rat(25086) cytochrome P450, family 2, subfamily e, polypeptide 1
  • sheep(100568285) cytochrome P450, family 2, subfamily E, polypeptide 1
  • domestic cat(554344) cytochrome P450 2E1
  • dog(415128) cytochrome P450, family 2, subfamily E, polypeptide 1
  • cow(282213) cytochrome P450, family 2, subfamily E, polypeptide 1
  • Horse(100066422) cytochrome P450, family 2, subfamily E, polypeptide 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CYP2E1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-CYP2E1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-CYP2E1, affinity isolated antibody,
Espèces réactives
human
Application
western blot
Anti-Cytochrome P450 Enzyme CYP2E1 Antibody, serum, Chemicon®,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

Cell Lines

Référence du produit
Description
Espèce(s)
CypExpress 2E1 Cytochrome P450 human, ,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
Cytochrome P450 human, 2E1 isozyme microsomes, with P450 Reductase and cytochrome b5, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CYP2E1,
Espèce(s)
human