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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

Synonymes:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
Espèces réactives
human
Application
western blot
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
Espèces réactives
mouse
Application
western blot
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunohistochemistry

inhibition assay

western blot
Anti-IKKa (p45) Antibody, clone 881H3, clone 881H3, from mouse,
Espèces réactives
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

Référence du produit
Description
Espèce(s)
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Chuk,
Espèce(s)
mouse
MISSION® esiRNA, targeting human CHUK,
Espèce(s)
human

Small Molecule - Substrate

Référence du produit
Description
Espèce(s)
IKK Substrate Peptide, ,
Espèce(s)
human