CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Synonymes:
BWCR, BWS, KIP2, WBS, p57, p57Kip2
Espèce(s):
Human CDKN1C (1028), Mouse Cdkn1c (12577), Rat Cdkn1c (246060), sheep CDKN1C (100216434), naked mole-rat Cdkn1c (101726530), cow CDKN1C (510972), Zebrafish cdkn1c (399483)
ID UniProtKB:
ID du gène:
- Human(1028) Summary: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
- Mouse(12577) cyclin-dependent kinase inhibitor 1C (P57)
- Rat(246060) cyclin-dependent kinase inhibitor 1C
- sheep(100216434) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- naked mole-rat(101726530) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- cow(510972) cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- Zebrafish(399483) cyclin-dependent kinase inhibitor 1C
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-p57 KIP2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
p57Kip2 (Kp10) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anti-CDKN1C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CDKN1C/p57 Kip2 Antibody, clone 6T4E6, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
western blot
Anti-Kip2 Antibody, Upstate®, from rabbit,
Espèces réactives
bovine, human
Application
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
esiRNA
Référence du produit
Description
Espèce(s)