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USP

Bromazepam

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-one

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About This Item

Empirical Formula (Hill Notation):
C14H10BrN3O
CAS Number:
Molecular Weight:
316.15
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

bromazepam

manufacturer/tradename

USP

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C(CN=C1C2=CC=CC=N2)NC3=C1C=C(Br)C=C3

InChI

1S/C14H10BrN3O/c15-9-4-5-11-10(7-9)14(17-8-13(19)18-11)12-3-1-2-6-16-12/h1-7H,8H2,(H,18,19)

InChI key

VMIYHDSEFNYJSL-UHFFFAOYSA-N

Gene Information

human ... GABRA2(2555)

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General description

Bromazepam belongs to the 1,4-benzodiazepine class of compounds. It is a type of psychotropic drug, which finds therapeutic applications as an anti-anxiety agent.

Application

Bromazepam may be used as a standard in the quantitative determination of bromazepam in biosamples like human plasma using high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS-MS).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Bromazepam determination in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: a highly sensitive and specific tool for bioequivalence studies
Laurito.LT, et al.
Journal of Mass Spectrometry : Jms, 39(2), 168-176 (2004)

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