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V3264

VDM 11

Name: VDM 11
Brand: SIGMA

≥98% (HPLC), oil

Synonym(s):

(5Z,8Z,11Z,14Z)-N-(4-Hydroxy-2-methylphenyl)-5,8,11,14-eicosatetraenamide, N-(4-Hydroxy-2-methylphenyl)arachidonylamide

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About This Item

Empirical Formula (Hill Notation):

C₂₇H₃₉NO₂

CAS Number:

313998-81-1

Molecular Weight:

409.60

MDL number:

MFCD04037552

UNSPSC Code:

12352202

PubChem Substance ID:

329829042

NACRES:

NA.77

description

Light-sensitive; store under argon.

Assay

≥98% (HPLC)

form

oil

color

gold

solubility

DMSO: soluble >5 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Nc1ccc(O)cc1C

InChI

1S/C27H39NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-27(30)28-26-22-21-25(29)23-24(26)2/h7-8,10-11,13-14,16-17,21-23,29H,3-6,9,12,15,18-20H2,1-2H3,(H,28,30)/b8-7-,11-10-,14-13-,17-16-

InChI key

WUZWFRWVRHLXHZ-ZKWNWVNESA-N

Biochem/physiol Actions

Potent, selective anandamide membrane transporter (AMT) inhibitor.

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302 + H312 + H332,H334

Precautionary Statements

P261 - P264 - P271 - P280 - P301 + P312 - P302 + P352 + P312

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Resp. Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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α2-Adrenoceptor agonist induces peripheral antinociception via the endocannabinoid system.

Thiago Roberto Lima Romero et al.

Pharmacological reports : PR, 72(1), 96-103 (2020-02-06)

Xylazine is an α2 adrenoceptor agonist that is extensively used in veterinary medicine and animal experimentation procedures to produce analgesia, sedation and muscle relaxation without causing general anesthesia. Considering the lack of knowledge of the mechanisms involved in peripheral antinociception

Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity.

L De Petrocellis et al.

FEBS letters, 483(1), 52-56 (2000-10-18)

Some synthetic agonists of the VR1 vanilloid (capsaicin) receptor also inhibit the facilitated transport into cells of the endogenous cannabinoid anandamide (arachidonoylethanolamide, AEA). Here we tested several AEA derivatives containing various derivatized phenyl groups or different alkyl chains as either

Contribution of Endocannabinoids to Intrinsic Motivation for Undirected Singing in Adult Zebra Finches.

Yunbok Kim et al.

Frontiers in physiology, 13, 882176-882176 (2022-05-03)

Songbirds, such as zebra finches, spontaneously produce many song renditions for vocal practice even in the absence of apparent recipients throughout their lives. Such "undirected singing" is driven by intrinsic motivation, which arises within individuals for internal satisfaction without immediate

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