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T9878

Sigma-Aldrich

Tyr-Leu

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About This Item

Empirical Formula (Hill Notation):
C15H22N2O4
CAS Number:
Molecular Weight:
294.35
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C(N)Cc1ccc(O)cc1)C(O)=O

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ying Chen et al.
The Analyst, 136(9), 1852-1858 (2011-03-12)
In this paper, we developed a simple and effective on-line focusing technique combining dynamic pH junction and sweeping by capillary electrophoresis (CE) with laser-induced fluorescence (LIF) detection. Dynamic pH junction-sweeping is defined when the sample has a different buffer pH
Takafumi Mizushige et al.
Neuroscience letters, 543, 126-129 (2013-04-11)
We previously reported that Tyr-Leu (YL) exhibits potent anxiolytic-like activity comparable to diazepam in mice. In the current study, we revealed that aromatic amino acid-Leu, Phe-Leu and Trp-Leu (FL and WL, respectively), exhibited anxiolytic-like activity in the elevated plus-maze and
Norimasa Kanegawa et al.
FEBS letters, 584(3), 599-604 (2009-12-17)
We found that Tyr-Leu (YL) dose-dependently exhibits potent anxiolytic-like activity (0.1-1mg/kg, i.p.) comparable to diazepam in the elevated plus-maze test in mice. YL was orally active (0.3-3mg/kg). A retro-sequence peptide or a mixture of Tyr and Leu was inactive. The
M M Mullally et al.
Biological chemistry Hoppe-Seyler, 377(4), 259-260 (1996-04-01)
Novel angiotensin-I-converting enzyme (ACE) inhibitory activities were detected in synthetic peptides corresponding to sequences of beta-lactoglobulin and alpha-lactalbumin and which are known to possess opioid activity. Using hippuryl-histidyl-leucine as substrate, the tetrapeptides beta-lactorphin (Tyr-Leu-Leu-Phe), alpha-lactorphin (Tyr-Gly-Leu-Phe) and beta-lactotensin (His-Ile-Arg-Leu) were
M L Gardner et al.
Quarterly journal of experimental physiology (Cambridge, England), 66(1), 17-24 (1981-01-01)
The peptide, N-benzoyl-L-tyrosyl-p-aminobenzoic acid, which is used in an oral test of pancreatic function, has been perfused through isolated rat small intestine in order to determine whether it can be absorbed across the intestine in intact form, and whether it

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