SRP6107
SOD-A from bacteria
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Synonym(s):
MnSOD, SOD2, Superoxide dismutase, manganese
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
biological source
bacterial
recombinant
expressed in E. coli
Assay
≥95% (SDS-PAGE)
form
liquid
mol wt
25.2 kDa (226 aa, 1-206 aa + His Tag)
packaging
pkg of 100 μg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
Escherichia coli K12 ... sodA(948403)
General description
Manganese-type superoxide dismutase, also known as SodA, is a member of the iron/manganese superoxide dismutase family.
Biochem/physiol Actions
Superoxide dismutase (SodA) destroys radicals which are normally produced within the cells and which are toxic to biological systems. It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase.
Physical form
1 mg/mL solution in 20 mM Tris-HCl (pH 8.0) containing 1 mM DTT, 0.1 M NaCl and 10% glycerol.
Preparation Note
Centrifuge the vial prior to opening.
Other Notes
MGSSHHHHHH SSGLVPRGSH MSYTLPSLPY AYDALEPHFD KQTMEIHHTK HHQTYVNNAN AALESLPEFA NLPVEELITK LDQLPADKKT VLRNNAGGHA NHSLFWKGLK KGTTLQGDLK AAIERDFGSV DNFKAEFEKA AASRFGSGWA WLVLKGDKLA VVSTANQDSP LMGEAISGAS GFPIMGLDVW EHAYYLKFQN RRPDYIKEFW NVVNWDEAAA RFAAKK
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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A manganese-rich environment supports superoxide dismutase activity in a Lyme disease pathogen, Borrelia burgdorferi.
Aguirre JD
The Journal of Biological Chemistry, 288(12), 8468-8478 (2013)
[Oxygen radicals-superoxide dismutase system and reproduction medicine].
Ishikawa M
Nihon Sanka Fujinka Gakkai Zasshi, 45(8), 842-848 (1993)
Oxidants, antioxidants and carcinogenesis.
Ray G and Husain SA
Indian Journal of Experimental Biology, 40(11), 1213-1232 (2002)
Carmen Cerchia et al.
Antioxidants (Basel, Switzerland), 11(4) (2022-04-24)
The microaerophile Streptococcus mutans, the main microaerophile responsible for the development of dental plaque, has a single cambialistic superoxide dismutase (SmSOD) for its protection against reactive oxygen species. In order to discover novel inhibitors of SmSOD, possibly interfering with the
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