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SML1709

Sigma-Aldrich

K6PC-5

≥98% (HPLC)

Synonym(s):

2-Hexyl-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-3-oxo-decanamide, K 6PC5;, N-(1,3-Dihydroxypropyl)-2-hexyl-3-oxo-decanamide

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5 MG
€129.00
25 MG
€521.00

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5 MG
€129.00
25 MG
€521.00

About This Item

Empirical Formula (Hill Notation):
C19H37NO4
CAS Number:
756875-51-1
Molecular Weight:
343.50
UNSPSC Code:
12352200
PubChem Substance ID:
329826032
NACRES:
NA.77

€129.00

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Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C(CCCCCCC)C(CCCCCC)C(NC(CO)CO)=O

InChI key

CGYVFCHCRBGGJG-UHFFFAOYSA-N

Biochem/physiol Actions

K6PC-5 is a potent and selective sphingosine kinase 1 (SphK1 or SK1) activator that increases keratin 1 and involucrin expression in normal human epidermal keratinocytes cultured in vitro. K6PC-5 promotes differentiation and proliferation of keratinocytes via intracellular Ca2+ signaling.
K6PC-5 is a potent and selective sphingosine kinase 1 (SphK1 or SK1) activator.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000401425
0000401425
086M4734V

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Michaela T Reichmann et al.
The Journal of clinical investigation, 131(15) (2021-06-16)
Tuberculosis (TB) is a persistent global pandemic, and standard treatment for it has not changed for 30 years. Mycobacterium tuberculosis (Mtb) has undergone prolonged coevolution with humans, and patients can control Mtb even after extensive infection, demonstrating the fine balance

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