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About This Item
Empirical Formula (Hill Notation):
C107H165N35O34S2
Molecular Weight:
2549.80
UNSPSC Code:
51111800
NACRES:
NA.32
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr
Application
Atrial natriuretic peptide(s) (ANP) (Atriopeptin) are peptide hormones that regulate vasodilation. The ANP fragment Atriopeptin III (ANP 127-150) is used to study the regulation of Na+/H+ exchange mediated in erythrocytes by cGMP/guanylate-cyclase activity.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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B M Schmitt et al.
Clinical and experimental pharmacology & physiology, 24(2), 131-138 (1997-02-01)
1. In mammalian plasma, many different inhibitors of Na+/K(+)-ATPase are present, but it is not clear whether their net effect on NA+/K(+)-ATPase activity changes during the regulation of electrolyte and fluid balance. We studied Na+/K(+)-ATPase inhibition by plasma extracts in
V Petrov et al.
European journal of biochemistry, 221(1), 195-199 (1994-04-01)
Human atrial natriuretic peptide (ANP) fragments ANP-(127-150) or ANP-III and ANP-(127-149) or ANP-II activate Na+/H+ exchange in human erythrocytes at concentrations as low as 1 pM. Both ANP-(127-147) or ANP-I and ANP-(129-150) or des-Ser5, Ser6-ANP-III have no effect on erythrocyte
V Petrov et al.
The American journal of physiology, 271(5 Pt 1), C1556-C1564 (1996-11-01)
Guanylate cyclase activity in human erythrocytes is investigated by evaluating the intracellular guanosine 3',5'-cyclic monophosphate (cGMP) content in the presence of various agents that exert specific effects on soluble or particulate guanylate cyclase. The increase in the intraerythrocyte cGMP content
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