SAB2501133

Anti-FEM1A (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-DKFZp762M136, Anti-EPRAP, fem-1 homolog a (C. elegans)
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, bovine, canine
• technique(s): indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: Q9BSK4
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... FEM1A(55527)

Description

General description

Fem-1 homolog A (FEM1A) is a homolog of the Fem-1 gene of Caenorhabditis elegans. It is predicted to encode an ankyrin repeat proteins which is expressed in many tissues. FEM1A is a conserved VHL-box protein. The gene encoding it is localized on human chromosome 19p13.3.

Immunogen

Peptide with sequence CGFIPEDLEAFIELH, from the C Terminus of the protein sequence according to NP_061178.1.

Biochem/physiol Actions

Fem-1 homolog A (FEM1A) is a substrate recognition subunit of cullin-2-RING E3 ubiquitin ligase complex. It has a role in the degradation of stem-loop binding protein (SLBP) and may be involved in anti-inflammatory signaling. FEM1A has been associated with polycystic ovary syndrome.

Features and Benefits

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Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable