Synthetic peptide directed towards the C terminal region of human ATAD1
Sequence
Synthetic peptide located within the following region: KQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVR
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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Maintenance of desmin intermediate filaments (IF) is vital for muscle plasticity and function, and their perturbed integrity due to accelerated loss or aggregation causes atrophy and myopathies. Calpain-1-mediated disassembly of ubiquitinated desmin IF is a prerequisite for desmin loss, myofibril
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