PLA0111

Rabbit anti-Lasu1/Ureb1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): ARF-BP1, ARF-binding protein 1, BJ-HCC-24 tumor antigen, HECT, HECT domain protein LASU1, HECTH9, HSPC272, Ib772, KIAA0312, LASU1, MULE, Mcl-1 ubiquitin ligase E3, UBA and WWE domain containing 1, UBA and WWE domain-containing protein 1, URE-B1, URE-binding protein 1, UREB1, homologous to E6AP carboxyl terminus homologous protein 9, large structure of UREB1, upstream regulatory element-binding protein 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: human
• technique(s): immunohistochemistry: 1:1000-1:5,000; immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000-1:10,000
• accession no.: NP_113584.3
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... Lasu1/Ureb1(10075)

Description

Immunogen

The epitope recognized by PLA0111 maps to a region between residues 1025 and 1075 of human Upstream Regulatory Element Binding Protein 1 using the numbering given in entry NP_113584.2 (GeneID 10075).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Lasu1/Ureb1 is an E3 ubiquitin protein ligase that mediates the ubiquitination of core histones, Mcl-1, Cdc6, and p53. Lasu1/Ureb1 expression is regulated during spermatogenesis and appears to play a role in chromatin modification in germ cells as well as other tissues.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable