P9180
Procaterol hydrochloride
Synonym(s):
erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1H)-quinolinone
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About This Item
Empirical Formula (Hill Notation):
C16H22N2O3 · HCl
CAS Number:
Molecular Weight:
326.82
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
form
powder
Quality Level
storage temp.
2-8°C
SMILES string
Cl.CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c2NC(=O)C=Cc12
InChI
1S/C16H22N2O3.ClH/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15;/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20);1H/t12-,16+;/m0./s1
InChI key
AEQDBKHAAWUCMT-CVHDTDHSSA-N
General description
Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.
Biochem/physiol Actions
β2-adrenoceptor agonist; bronchodilator.
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Yukiko Hiraguchi et al.
International archives of allergy and immunology, 155 Suppl 1, 85-89 (2011-06-10)
Viral respiratory tract infections play an important role in the inception and exacerbation of asthma. Eosinophils, major effector cells in asthma, often accumulate in the airways during viral infections and are possibly activated by respiratory RNA viruses through Toll-like receptor
Ethanolamines: Advances in Research and Application (2012)
F Preitner et al.
British journal of pharmacology, 124(8), 1684-1688 (1998-10-02)
The beta3-adrenoceptor plays an important role in the adrenergic response of brown and white adipose tissues (BAT and WAT). In this study, in vitro metabolic responses to beta-adrenoceptor stimulation were compared in adipose tissues of beta3-adrenoceptor knockout and wild type
Mutsuo Yamaya et al.
European journal of pharmacology, 650(1), 431-444 (2010-10-14)
β(2) agonists reduce the frequency of exacerbations in patients with bronchial asthma and chronic obstructive pulmonary disease caused by respiratory virus infection. β(2) agonists reduce the production of pro-inflammatory cytokines. However, the inhibitory effects of β(2) agonists on the infection
Guixin Li et al.
The Analyst, 134(7), 1396-1404 (2009-06-30)
A novel space- and time-resolved photo-induced chemiluminescence (PICL) analytical method was developed based on the photocatalysis of the Co2+-doped TiO2 nanoparticles. The PICL reaction procedure under the photocatalysis of Co2+-doped TiO2 nanoparticles was investigated using cyclic voltammetry and potentiometry. Meanwhile
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