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Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 26(4), 504-512 (2007-12-01)
Damage or loss of the meniscus is associated with progressive osteoarthritic degeneration of the knee joint. Injured and degenerative joints are characterized by elevated levels of the pro-inflammatory cytokine interleukin-1 (IL-1), which with prolonged exposure can induce catabolic and anti-anabolic
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