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H0501

Sigma-Aldrich

DL-Homocystine

≥98% (TLC)

Synonym(s):

meso-4,4′-Dithio-bis(2-aminobutanoic acid)

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About This Item

Linear Formula:
HOOCCH(NH2)CH2CH2SSCH2CH2CH(NH2)COOH
CAS Number:
870-93-9
Molecular Weight:
268.35
Beilstein:
1728581
EC Number:
212-803-5
MDL number:
MFCD00069587
UNSPSC Code:
12352209
eCl@ss:
42021308
PubChem Substance ID:
24895403
NACRES:
NA.26

product name

DL-Homocystine,

Assay

≥98% (TLC)

form

powder

color

white to off-white

mp

>300 °C

application(s)

detection

SMILES string

N[C@H](CCSSCC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6+

InChI key

ZTVZLYBCZNMWCF-OLQVQODUSA-N

Gene Information

human ... BHMT(635)

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sezgin Bakirdere et al.
Analytica chimica acta, 680(1-2), 41-47 (2010-10-26)
An analytical method was developed for the determination of thiols in biological samples. Reverse phase chromatography coupled to ICP quadrupole MS or Orbitrap MS was employed for the separation and detection of thiols. For the determination of total thiols, oxidized
Lei Li et al.
Amino acids, 50(10), 1485-1494 (2018-08-01)
Plasma homocysteine is elevated in patients with impaired renal function, and markedly so at end-stage renal disease. As chronic kidney disease and hyperhomocysteinemia are also independent risk factors for cardiovascular disease, the latter is hypothesized to accelerate vascular abnormalities following
K Yokoi et al.
The Journal of nutrition, 131(4), 1302-1308 (2001-04-04)
The effect of dietary sulfur amino acids on bioelectric properties was studied in rats by using bioimpedance spectroscopy. Weanling rats were assigned to one of 12 groups in a factorially arranged experiment with dietary variables of supplemental sulfur amino acid
Javier Escobar et al.
Journal of pharmaceutical and biomedical analysis, 123, 104-112 (2016-02-20)
The aminothiols are biological compounds with numerous vital functions. One of the most relevant is their role as antioxidant systems. The reduced to oxidized ratios are extremely useful indicators of oxidative stress and cellular redox status. We have validated an
Chasity B Love-Nkansah et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 22(3), 934-940 (2015-11-05)
Homocysteine sulfinyl radical ((SO⋅) Hcy) is a reactive intermediate involved during oxidative damage of DNA in the presence of high concentrations of homocysteine (Hcy). The short lifetime of (SO⋅) Hcy makes its preparation, isolation, and characterization challenging using traditional chemical
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