This is a dual-component product. A single molecular weight does not apply. The molecular weight of the B-estradiol is 272.38 grams per mol, and the molecular weight of the 2-hydroxypropyl-β-cyclodextrin is 1396 grams per mol. The package size of 100 mg is in reference to the B-Estradiol. This product contains 40 - 50 mg per gram solid. The lot-specific B-estradiol content is reported in the Certificate of Analysis.
E4389
β-Estradiol-Water Soluble
BioReagent, suitable for cell culture
Synonym(s):
Cyclodextrin-encapsulated 17β-estradiol
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100 MG
€347.00
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100 MG
€347.00
About This Item
biological source:
synthetic (organic)
form:
powder
Recommended Products
biological source
synthetic (organic)
Quality Level
sterility
non-sterile
product line
BioReagent
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 25 mg/mL, clear to slightly hazy
shipped in
ambient
storage temp.
room temp
SMILES string
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O.C[C@@H]5[C@@H](O)[C@@H]6O[C@H](CO)[C@H]5O[C@H]7O[C@H](CO)[C@@H](O[C@H]8O[C@H](CO)[C@@H](O[C@H]9O[C@H](CO)[C@@H](O[C@H]%10O[C@H](CO)[C@@H](O[C@H]%11O[C@H](CO)[C@@H](O[C@H]%12O[C@H](CO)[C@@H](O6)[C@H](O)[C@H]%12O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8OCCCO)[C@H](O)[C@H]7O
InChI
1S/C46H78O35.C18H24O2/c1-12-20(55)40-68-13(5-48)32(12)75-41-26(61)25(60)37(18(10-53)69-41)81-46-39(67-4-2-3-47)31(66)38(19(11-54)74-46)80-45-30(65)24(59)36(17(9-52)73-45)79-44-29(64)23(58)35(16(8-51)72-44)78-43-28(63)22(57)34(15(7-50)71-43)77-42-27(62)21(56)33(76-40)14(6-49)70-42;1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h12-66H,2-11H2,1H3;3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31+,32+,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-;14-,15-,16+,17+,18+/m11/s1
InChI key
XMURHKLFGRLVRW-JKDYGSMVSA-N
General description
β-estradiol is a natural human estrogen. It is vital for the growth of breast and reproductive epithelia, maturation of long bones and development of secondary sexual characteristics.[1] Estradiol is produced by immature germ cells, spermatozoa, Leydig cells and Sertoli cells.[2] β-estradiol acts as a menopausal hormones. It is involved in replacement therapy for female hypogonadism or primary ovarian failure. Reduced levels of β-estradiol are linked to heart disease and osteoporosis.[1] Estradiol plays a critical role in proliferation, modulation of ion transport and control of apoptosis in Sertoli cells. It maintains sperm concentration, motility and morphology.[2]
Application
Packaging
Package size based on estradiol
Other Notes
Contains 40-55 mg estradiol per gram of solid; balance 2-hydroxypropyl-β-cyclodextrin.
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Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
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what is the molecular weight of E-4389 product?
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What is the storage stability of E4389, β-Estradiol - Water Soluble (25 mg/mL complex) in distilled water at 4C, -20C, or -80C?
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This product is stable for 6 months at -20°C in a non-defrosting freezer after solubilizing in distilled water. There is no stability data for this product at 4°C or -80°C.
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How do I calculate the molarity of product E4389, β-Estradiol - Water Soluble?
1 answer-
Product E4389 (β-Estradiol-Water Soluble) is a complex of β-Estradiol and cyclodextrin. Cyclodextrin is used to aid in the solubility of β-Estradiol into water. In order to prepare a molar solution of β-Estradiol you will have to base it on the β-Estradiol content in the solution and not the entire complex.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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